| Course title: Microbiology A
(Department of Laboratory Medicine) |
| Name of lecturer: Assist.
Professor A. Psaroulaki, Assist. Professor E. Scoulica,
Assist. Prof. M. Antoniou. |
| Course
code: 4.4 Micro. A |
Type of
course: Compulsory |
Level of
course: Elementary |
| Year of
study: Second |
Semester:
Spring |
Number of
credits (ECTS): 5.5 |
|
Objectives:
• Teaching of General Microbiology at basic level
(structure, morphology, metabolism and physiology of
microorganisms), and analysis of basic concepts of
Medical Microbiology prerequisite for understanding the
role of microorganisms as causative agents of infectious
diseases.
• The understanding of: a) interaction of
organism/host-microorganism, as well as basic pathogenic
mechanisms of microorganisms b) modes of transmission
and spread of microorganisms and their adaptation to the
host environment and c) the principles and methodologies
in laboratory diagnosis, treatment, prophylaxis and
control of microorganisms that are considered to be
causative agents of infections.
• The systematic study of bacteria of medical interest
|
|
Prerequisites:
None
|
|
Course
contents:
General Principles of
Medical Microbiology
• The Evolution of Medical Microbiology. The etiological
agents of infectious diseases. Phylogeny, Classification
and Nomenclature of microorganisms.
• Bacteria-host interactions: The normal microbial
flora. Pathogen survival strategies in host organisms.
Pathogenicity and virulence of microorganisms. Toxins
and their mode of action.
• Basic epidemiology of infections: Transmission and
spread of infectious agents. Epidemiological
investigation of infections -Methods to investigate
endemics and epidemics- Epidemiological markers.
Surveillance and Prevention Control of infectious
diseases and the role of the International
Organizations.
• Means of microbial destruction and control of
pathogenic microorganisms (Sterilization, Disinfection,
Antisepsis). The use of disinfectants and the resistance
mechanisms.
• Diagnostic Microbiology: Microorganisms in the
laboratory. General principles of laboratory diagnosis
of infections (Phenotypic, serological, molecular
diagnostics)
Bacteriology
• Introduction to bacteriology: General Properties of
bacteria. Cell biology- Bacterial morphology and
structure. Bacterial genetics.
• Bacterial nutrition growth and metabolism. Methods of
growth and identification of microorganisms.
• Antimicrobials-Antibiotics: Mechanism of action of
anti-microbial drugs. Resistance mechanisms of bacteria
to anti-microbial drugs. Laboratory investigation of
antibiotic resistance
Systematic Bacteriology
Enterobacteriaceae. Pseudomonas. Campylobacter,
Helicobacter. Vibrios and Aeromonas sp. Legionella.
Bacilli. Listeria. Anaerobic / Bacteroides
|
|
Recommended
reading: "Medical Microbiology", 5th edition, Patrik R.
Murray; Ken S. Rosenthal and Michael A. Pfaller, 2005.
|
|
Teaching
methods: Lectures and tutorials
|
| Assessment
methods: Written or oral examination |
| Language of
instruction: Greek |